Euro--Extra Credit

The first Two correct responses will receive TWO  extra assessment points for their test. "Explain why the Italian City States that were the center of the renaissance and economic growth of the 14th and 15th century will further fall in to decline after the portuguese successfully sail south of Africa to Asia." AND----thinking ahead WHY would the Catholic Church and Spain see it is as a priority to send Catholic missionaries to the western hemisphere??!(The americas) GO  This is available 'til 9pm or until i get two correct responses